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Inhibition of SDF-1/CXCR4 Axis to Alleviate Abnormal Bone Formation and Angiogenesis Could Improve the Subchondral Bone Microenvironment in Osteoarthritis

The pathogenesis of the osteoarthritis (OA) is complex. Abnormal subchondral bone metabolism is an important cause of this disease. Further understanding on the pathology of the subchondral bone in OA may provide a new therapy. This research is about to investigate the role of SDF-1 in the subchondr...

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Detalles Bibliográficos
Publicado en:Biomed Res Int
Main Authors: Qin, Hanjun, Zhao, Xingqi, Hu, Yan Jun, Wang, Shengnan, Ma, Yunfei, He, Siying, Shen, Ke, Wan, Haoyang, Cui, Zhuang, Yu, Bin
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179778/
https://ncbi.nlm.nih.gov/pubmed/34136574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/8852574
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