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Phenformin promotes keratinocyte differentiation via the calcineurin/NFAT pathway
Phenformin is a drug in the biguanide class that was previously used to treat type 2 diabetes. We have reported the anti-tumor activities of phenformin to enhance the efficacy of BRAF-MEK-ERK pathway inhibition and to inhibit myeloid-derived suppressor cells in various melanoma models. Here we demon...
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| 出版年: | J Invest Dermatol |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8179313/ https://ncbi.nlm.nih.gov/pubmed/32619504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2020.05.114 |
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