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Intermediates involved in serotonin oxidation catalyzed by Cu bound Aβ peptides

The degradation of neurotransmitters is a hallmark feature of Alzheimer's disease (AD). Copper bound Aβ peptides, invoked to be involved in the pathology of AD, are found to catalyze the oxidation of serotonin (5-HT) by H(2)O(2). A combination of EPR and resonance Raman spectroscopy reveals the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Nath, Arnab Kumar, Ghatak, Arnab, Dey, Abhishek, Dey, Somdatta Ghosh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society of Chemistry 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179298/
https://ncbi.nlm.nih.gov/pubmed/34163956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc06258h
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