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Formation of compound I in heme bound Aβ-peptides relevant to Alzheimer's disease
Proteolysis of Amyloid Precursor Protein, APP, results in the formation of amyloid β (Aβ) peptides, which have been associated with Alzheimer's disease (AD). Recently the failure of therapeutic agents that prohibit Aβ aggregation and sequester Cu/Zn in providing symptomatic relief to AD patient...
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| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6844219/ https://ncbi.nlm.nih.gov/pubmed/31803419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc01679a |
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