Pyridylic anions are soft nucleophiles in the palladium-catalyzed C(sp(3))–H allylation of 4-alkylpyridines

We report a mild palladium-catalyzed method for the selective allylation of 4-alkylpyridines in which highly basic pyridylic anions behave as soft nucleophiles. This method exploits alkylidene dihydropyridines, which are semi-stable intermediates readily formed using a ‘soft-enolization’ approach, i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Sci
Prif Awduron: Wasfy, Nour, Rasheed, Faizan, Robidas, Raphaël, Hunter, Isabelle, Shi, Jiaqi, Doan, Brian, Legault, Claude Y., Fishlock, Dan, Orellana, Arturo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Royal Society of Chemistry 2020
Pynciau:
Chemistry
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8179045/
https://ncbi.nlm.nih.gov/pubmed/34163914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc03304a
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg