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Single point activation of pyridines enables reductive hydroxymethylation
The single point activation of pyridines, using an electron-deficient benzyl group, facilitates the ruthenium-catalysed dearomative functionalisation of a range of electronically diverse pyridine derivatives. This transformation delivers hydroxymethylated piperidines in good yields, allowing rapid a...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society of Chemistry
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178984/ https://ncbi.nlm.nih.gov/pubmed/34163807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc05656a |
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