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Reductive Hydroxymethylation of 4‐Heteroarylpyridines
The activation of pyridinium salts with electron‐withdrawing heterocycles enables an iridium‐catalyzed reductive hydroxymethylation reaction to proceed smoothly, facilitating the preparation of useful 3D heteroaryl‐substituted functionalized piperidines. The methodology is used to prepare 3‐hydroxym...
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| Publicado no: | Chemistry |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7754387/ https://ncbi.nlm.nih.gov/pubmed/31917881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202000060 |
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