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High-throughput discovery and characterization of human transcriptional effectors
Thousands of proteins localize to the nucleus; however, it remains unclear which contain transcriptional effectors. Here, we develop HT-recruit - a pooled assay where protein libraries are recruited to a reporter, and their transcriptional effects are measured by sequencing. Using this approach, we...
Zapisane w:
| Wydane w: | Cell |
|---|---|
| Główni autorzy: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178797/ https://ncbi.nlm.nih.gov/pubmed/33326746 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2020.11.024 |
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