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Engineered prime editors with PAM flexibility
Although prime editors are a powerful tool for genome editing, which can generate various types of mutations such as nucleotide substitutions, insertions, and deletions in the genome without double-strand breaks or donor DNA, the conventional prime editors are still limited to their target scopes be...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178456/ https://ncbi.nlm.nih.gov/pubmed/33636398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.02.022 |
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