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Engineered prime editors with PAM flexibility

Although prime editors are a powerful tool for genome editing, which can generate various types of mutations such as nucleotide substitutions, insertions, and deletions in the genome without double-strand breaks or donor DNA, the conventional prime editors are still limited to their target scopes be...

詳細記述

保存先:
書誌詳細
出版年:Mol Ther
主要な著者: Kweon, Jiyeon, Yoon, Jung-Ki, Jang, An-Hee, Shin, Ha Rim, See, Ji-Eun, Jang, Gayoung, Kim, Jong-Il, Kim, Yongsub
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Gene & Cell Therapy 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178456/
https://ncbi.nlm.nih.gov/pubmed/33636398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.02.022
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