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Imbalance of TGF-β1/BMP-7 pathways induced by M2-polarized macrophages promotes hepatocellular carcinoma aggressiveness

The transforming growth factor-beta (TGF-β) signaling pathway is the predominant cytokine signaling pathway in the development and progression of hepatocellular carcinoma (HCC). Bone morphogenetic protein (BMP), another member of the TGF-β superfamily, has been frequently found to participate in cro...

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Dettagli Bibliografici
Pubblicato in:Mol Ther
Autori principali: Ning, Junya, Ye, Yingnan, Bu, Dechao, Zhao, Gang, Song, Tianqiang, Liu, Pengpeng, Yu, Wenwen, Wang, Hailong, Li, Hui, Ren, Xiubao, Ying, Guoguang, Zhao, Yi, Yu, Jinpu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178441/
https://ncbi.nlm.nih.gov/pubmed/33601054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2021.02.016
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