Neurotensin/IL-8 pathway orchestrates local inflammatory response and tumor invasion by inducing M2 polarization of Tumor-Associated macrophages and epithelial-mesenchymal transition of hepatocellular carcinoma cells

We previously demonstrated that neurotensin (NTS) induces local inflammation and promotes tumor invasion in hepatocellular carcinoma (HCC). However, the underlying molecular mechanisms are not clear. In this study, positive correlations between NTS and interleukin (IL)-8 were identified at both the...

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Vydáno v:Oncoimmunology
Hlavní autoři: Xiao, Pei, Long, Xinxin, Zhang, Lijie, Ye, Yingnan, Guo, Jincheng, Liu, Pengpeng, Zhang, Rui, Ning, Junya, Yu, Wenwen, Wei, Feng, Yu, Jinpu
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993481/
https://ncbi.nlm.nih.gov/pubmed/29900041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1440166
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