Neurotensin/IL-8 pathway orchestrates local inflammatory response and tumor invasion by inducing M2 polarization of Tumor-Associated macrophages and epithelial-mesenchymal transition of hepatocellular carcinoma cells

We previously demonstrated that neurotensin (NTS) induces local inflammation and promotes tumor invasion in hepatocellular carcinoma (HCC). However, the underlying molecular mechanisms are not clear. In this study, positive correlations between NTS and interleukin (IL)-8 were identified at both the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Xiao, Pei, Long, Xinxin, Zhang, Lijie, Ye, Yingnan, Guo, Jincheng, Liu, Pengpeng, Zhang, Rui, Ning, Junya, Yu, Wenwen, Wei, Feng, Yu, Jinpu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993481/
https://ncbi.nlm.nih.gov/pubmed/29900041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1440166
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