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The Hippo Pathway Effector YAP Promotes Ferroptosis via the E3 Ligase SKP2
Ferroptosis is a new form of regulated cell death resulting from the accumulation of lipid-reactive oxygen species (ROS). A growing number of studies indicate ferroptosis as an important tumor suppressor mechanism having therapeutic potential in cancers. Previously, we identified TAZ, a Hippo pathwa...
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| Gepubliceerd in: | Mol Cancer Res |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2021
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8178191/ https://ncbi.nlm.nih.gov/pubmed/33707306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-20-0534 |
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