DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

Recurrent breast cancer presents significant challenges with aggressive phenotypes and treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report that murine recurrent breast tumor cells, when compared with primary tumor cells, are highly sensitive to ferroptosis. Disco...

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Библиографические подробности
Опубликовано в: :Oncogene
Главные авторы: Lin, Chao-Chieh, Yang, Wen-Hsuan, Lin, Yi-Tzu, Tang, Xiaohu, Chen, Po-Han, Ding, Chien-Kuang Cornelia, Qu, Dan Chen, Alvarez, James V., Chi, Jen-Tsan
Формат: Artigo
Язык:Inglês
Опубликовано: 2021
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988308/
https://ncbi.nlm.nih.gov/pubmed/33603168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01676-x
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