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DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

Recurrent breast cancer presents significant challenges with aggressive phenotypes and treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report that murine recurrent breast tumor cells, when compared with primary tumor cells, are highly sensitive to ferroptosis. Disco...

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Vydáno v:Oncogene
Hlavní autoři: Lin, Chao-Chieh, Yang, Wen-Hsuan, Lin, Yi-Tzu, Tang, Xiaohu, Chen, Po-Han, Ding, Chien-Kuang Cornelia, Qu, Dan Chen, Alvarez, James V., Chi, Jen-Tsan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988308/
https://ncbi.nlm.nih.gov/pubmed/33603168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01676-x
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