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DDR2 upregulation confers ferroptosis susceptibility of recurrent breast tumors through the Hippo pathway

Recurrent breast cancer presents significant challenges with aggressive phenotypes and treatment resistance. Therefore, novel therapeutics are urgently needed. Here, we report that murine recurrent breast tumor cells, when compared with primary tumor cells, are highly sensitive to ferroptosis. Disco...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Lin, Chao-Chieh, Yang, Wen-Hsuan, Lin, Yi-Tzu, Tang, Xiaohu, Chen, Po-Han, Ding, Chien-Kuang Cornelia, Qu, Dan Chen, Alvarez, James V., Chi, Jen-Tsan
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988308/
https://ncbi.nlm.nih.gov/pubmed/33603168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-021-01676-x
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