Epigenetic and post-transcriptional modulation of SOS1 can promote breast cancer metastasis through obesity-activated c-Met signaling in African American women

Ethnicity is considered to be one of the major risk factors in certain subtypes of breast cancer. However, the mechanism of this racial disparity remains poorly understood. Here we demonstrate that SOS1, a key regulator of Ras pathway, is highly expressed in African American (AA) breast cancer patie...

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Detaylı Bibliyografya
Yayımlandı:Cancer Res
Asıl Yazarlar: Xing, Fei, Zhao, Dan, Wu, Shih‐Ying, Tyagi, Abhishek, Wu, Kerui, Sharma, Sambad, Liu, Yin, Deshpande, Ravindra, Wang, Yuezhu, Cleary, Jacob, Miller, Lance D., Chittiboyina, Amar G., Yalamanchili, Chinni, Mo, Yin-Yuan, Watabe, Kounosuke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8178187/
https://ncbi.nlm.nih.gov/pubmed/33446575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-4031
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