Assessment of cognitive and neural recovery in survivors of pediatric brain tumors in a pilot clinical trial using metformin

We asked whether pharmacological stimulation of endogenous neural precursor cells (NPCs) may promote cognitive recovery and brain repair, focusing on the drug metformin, in parallel rodent and human studies of radiation injury. In the rodent cranial radiation model, we found that metformin enhanced...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Med
Päätekijät: Ayoub, Ramy, Ruddy, Rebecca M., Cox, Elizabeth, Oyefiade, Adeoye, Derkach, Daniel, Laughlin, Suzanne, Ades-aron, Benjamin, Shirzadi, Zahra, Fieremans, Els, Macintosh, Bradley J., de Medeiros, Cynthia B., Skocic, Jovanka, Bouffet, Eric, Miller, Freda D., Morshead, Cindi M., Mabbott, Donald J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176964/
https://ncbi.nlm.nih.gov/pubmed/32719487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-020-0985-2
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia