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The molecular and epigenetic mechanisms of innate lymphoid cell (ILC) memory and its relevance for asthma
Repetitive exposure of Rag1(−/−) mice to the Alternaria allergen extract generated a form of memory that elicited an asthma-like response upon a subthreshold recall challenge 3–15 wk later. This memory was associated with lung ICOS(+)ST2(+) ILC2s. Genetic, pharmacologic, and antibody-mediated inhibi...
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| Publicat a: | J Exp Med |
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| Autors principals: | , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Rockefeller University Press
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8176441/ https://ncbi.nlm.nih.gov/pubmed/34076685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20201354 |
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