Steroid Resistance of Airway Type 2 Innate Lymphoid Cells (ILC2s) from Severe Asthma: The Role of Thymic Stromal cell Lymphopoietin (TSLP)

BACKGROUND: ILC2s represent an important type 2 immune cell. Glucocorticoid regulation of human ILC2s is largely unknown. OBJECTIVE: To assess steroid resistance of human blood and airway ILC2s from asthmatic patients and examine its mechanism of induction. METHODS: We studied human blood and lung I...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Liu, Sucai, Verma, Mukesh, Michalec, Lidia, Liu, Weimin, Sripada, Anand, Rollins, Donald, Good, James, Ito, Yoko, Chu, HongWei, Gorska, Magdalena M., Martin, Richard J., Alam, Rafeul
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650571/
https://ncbi.nlm.nih.gov/pubmed/28433687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.03.032
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