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Luteolin promotes macrophage-mediated phagocytosis by inhibiting CD47 pyroglutamation
‘Don't eat me’ signal of CD47 is activated via its interaction with SIRPα protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-peptide cyclotransferase-like protein (isoQC) takes an...
Gorde:
| Argitaratua izan da: | Transl Oncol |
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| Egile Nagusiak: | , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Neoplasia Press
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8176368/ https://ncbi.nlm.nih.gov/pubmed/34051623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101129 |
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