Activation of the intracellular pattern-recognition receptor NOD2 promotes acute myeloid leukemia cell apoptosis and provides a survival advantage in an animal model of AML

Toll-like receptors (TLRs), a family of membrane-bound pattern recognition receptors (PRRs) found on innate immune cells, have been well studied in the context of cancer therapy. Activation of these receptors has been shown to induce inflammatory anti-cancer events, including differentiation and apo...

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Udgivet i:J Immunol
Main Authors: Buteyn, Nathaniel J., Santhanam, Ramasamy, Merchand-Reyes, Giovanna, Murugesan, Rakesh A., Dettorre, Gino M., Byrd, John C., Sarkar, Anasuya, Vasu, Sumithira, Mundy-Bosse, Bethany L., Butchar, Jonathan P., Tridandapani, Susheela
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176195/
https://ncbi.nlm.nih.gov/pubmed/32094205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900885
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