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Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNγ response

Tularemia is a zoonotic disease caused by the Gram-negative intracellular pathogen Francisella tularensis. These bacteria evade phagolysosomal fusion, escape from the phagosome and replicate in the host cell cytoplasm. IFNγ has been shown to suppress the intra-macrophage growth of Francisella throug...

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Detalhes bibliográficos
Main Authors: Parsa, Kishore V. L., Butchar, Jonathan P., Rajaram, Murugesan V. S., Cremer, Thomas J., Gunn, John S., Schlesinger, Larry S., Tridandapani., Susheela
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577832/
https://ncbi.nlm.nih.gov/pubmed/18514317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.04.006
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