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The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk

Francisella tularensis is a highly infectious, Gram-negative intra-cellular pathogen that can cause the zoonotic disease tularemia. Although the receptors critical for internalization of Francisella by macrophages are beginning to be defined, the identity of the downstream signaling pathways essenti...

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Bibliographic Details
Main Authors: Parsa, Kishore V. L., Butchar, Jonathan P., Rajaram, Murugesan V. S., Cremer, Thomas J., Tridandapani., Susheela
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408723/
https://ncbi.nlm.nih.gov/pubmed/18295889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2008.01.011
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