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A primate-specific RNA-binding protein (RBMXL3) is involved in glucocorticoid regulation of human pulmonary surfactant protein B (SP-B) mRNA stability

The ability of pulmonary surfactant to reduce alveolar surface tension requires adequate levels of surfactant protein B (SP-B). Dexamethasone (DEX) increases human SP-B expression, in part, through increased SP-B mRNA stability. A 30-nt-long hairpin element (RBE) in the 3′-untranslated region of hum...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Lung Cell Mol Physiol
Prif Awduron: Liu, Lidan, Liu, Xiangli, Bi, Weizhen, Alcorn, Joseph L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174829/
https://ncbi.nlm.nih.gov/pubmed/33719563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00022.2020
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