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Glucocorticoid regulation of human pulmonary surfactant protein-B (SP-B) mRNA stability is independent of activated glucocorticoid receptor

Adequate expression of surfactant protein-B (SP-B) is critical in the function of pulmonary surfactant to reduce alveolar surface tension. Expression of SP-B mRNA is restricted to specific lung-airway epithelial cells, and human SP-B mRNA stability is increased in the presence of the synthetic gluco...

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Detalhes bibliográficos
Main Authors: Tillis, Ceá C., Huang, Helen W., Bi, Weizhen, Pan, Su, Bruce, Shirley R., Alcorn, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119123/
https://ncbi.nlm.nih.gov/pubmed/21398497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00420.2010
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