The Prognostic Impact of Intratumoral Aryl Hydrocarbon Receptor in Primary Breast Cancer Depends on the Type of Endocrine Therapy: A Population-Based Cohort Study

The aryl hydrocarbon receptor (AhR) is a master regulator of multiple pathways involved in breast cancer, and influences the estrogen receptor alpha (ER) and aromatase/CYP19A1. The purpose of this study was to elucidate the interplay between intratumoral levels of AhR and aromatase, patient characte...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Tryggvadottir, Helga, Sandén, Emma, Björner, Sofie, Bressan, Alessandra, Ygland Rödström, Maria, Khazaei, Somayeh, Edwards, Dean P., Nodin, Björn, Jirström, Karin, Isaksson, Karolin, Borgquist, Signe, Jernström, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174786/
https://ncbi.nlm.nih.gov/pubmed/34094928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.642768
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