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Oncohistone mutations enhance chromatin remodeling and alter cell fates
Whole genome sequencing data mining efforts have revealed numerous histone mutations in a wide range of cancer types. These occur in all four core histones in both the tail and globular domains and remain largely uncharacterized. Here we used two high-throughput approaches, a DNA-barcoded mononucleo...
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| Publicado no: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8174649/ https://ncbi.nlm.nih.gov/pubmed/33649601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-021-00738-1 |
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