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Resolvin D1 enhances necroptotic cell clearance through promoting macrophage fatty acid oxidation and oxidative phosphorylation

OBJECTIVES: Plaque necrosis is a key feature of defective resolution in atherosclerosis. Recent evidence suggests that necroptosis promotes plaque necrosis, therefore we sought to determine how necroptotic cells (NCs) impact resolution programs in plaques. APPROACHES AND RESULTS: To investigate the...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Hosseini, Zeinab, Marinello, Michael, Decker, Christa, Sansbury, Brian E., Sadhu, Sudeshna, Gerlach, Brennan D., Ramos, Ramon Bossardi, Adam, Alejandro P., Spite, Matthew, Fredman, Gabrielle
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174560/
https://ncbi.nlm.nih.gov/pubmed/33472399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.120.315758
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