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Structure-based virtual screening of highly potent inhibitors of the nematode chitinase CeCht1

Nematode chitinases play vital roles in various physiological processes, including egg hatching, larva moulting, and reproduction. Small-molecule inhibitors of nematode chitinases have potential applications for controlling nematode pests. On the basis of the crystal structure of CeCht1, a represent...

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Detalles Bibliográficos
Publicado en:J Enzyme Inhib Med Chem
Main Authors: Chen, Wei, Chen, Qi, Kumar, Ashutosh, Jiang, Xi, Zhang, Kam Y. J., Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8174485/
https://ncbi.nlm.nih.gov/pubmed/34074203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1931862
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