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Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition

Small-molecule inhibitors of insect chitinases have potential applications for controlling insect pests. Insect group II chitinase (ChtII) is the most important chitinase in insects and functions throughout all developmental stages. However, the possibility of inhibiting ChtII by small molecules has...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Wei, Zhou, Yong, Yang, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579453/
https://ncbi.nlm.nih.gov/pubmed/31053640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007812
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