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Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition

Small-molecule inhibitors of insect chitinases have potential applications for controlling insect pests. Insect group II chitinase (ChtII) is the most important chitinase in insects and functions throughout all developmental stages. However, the possibility of inhibiting ChtII by small molecules has...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Chen, Wei, Zhou, Yong, Yang, Qing
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6579453/
https://ncbi.nlm.nih.gov/pubmed/31053640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007812
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