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Optimization of protocols for pre-embedding immunogold electron microscopy of neurons in cell cultures and brains

Immunogold labeling allows localization of proteins at the electron microscopy (EM) level of resolution, and quantification of signals. The present paper summarizes methodological issues and experiences gained from studies on the distribution of synaptic and other neuron-specific proteins in cell cu...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Tao-Cheng, Jung-Hwa, Crocker, Virginia, Moreira, Sandra Lara, Azzam, Rita
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173732/
https://ncbi.nlm.nih.gov/pubmed/34082785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00799-2
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