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Enriched pharmacokinetic behavior and antitumor efficacy of thymoquinone by liposomal delivery

BACKGROUND: Thymoquinone (TQ) has potential anti-inflammatory, immunomodulatory and anticancer effects but its clinical use is limited by its low solubility, poor bioavailability and rapid clearance. AIM: To enhance systemic bioavailability and tumor-specific toxicity of TQ. MATERIALS & METHODS:...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Nanomedicine (Lond)
Autori principali: Rachamalla, Hari Krishnareddy, Bhattacharya, Santanu, Ahmad, Ajaz, Sridharan, Kathyayani, Madamsetty, Vijay Sagar, Mondal, Sujan Kumar, Wang, Enfeng, Dutta, Shamit K, Jan, Basit L, Jinka, Sudhakar, Chandra Sekhar Jaggarapu, Madan Mohan, Yakati, Venu, Mukhopadhyay, Debabrata, Alkharfy, Khalid M, Banerjee, Rajkumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2021
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173500/
https://ncbi.nlm.nih.gov/pubmed/33769068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2020-0470
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