Enriched pharmacokinetic behavior and antitumor efficacy of thymoquinone by liposomal delivery

BACKGROUND: Thymoquinone (TQ) has potential anti-inflammatory, immunomodulatory and anticancer effects but its clinical use is limited by its low solubility, poor bioavailability and rapid clearance. AIM: To enhance systemic bioavailability and tumor-specific toxicity of TQ. MATERIALS & METHODS:...

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Detalhes bibliográficos
Publicado no:Nanomedicine (Lond)
Main Authors: Rachamalla, Hari Krishnareddy, Bhattacharya, Santanu, Ahmad, Ajaz, Sridharan, Kathyayani, Madamsetty, Vijay Sagar, Mondal, Sujan Kumar, Wang, Enfeng, Dutta, Shamit K, Jan, Basit L, Jinka, Sudhakar, Chandra Sekhar Jaggarapu, Madan Mohan, Yakati, Venu, Mukhopadhyay, Debabrata, Alkharfy, Khalid M, Banerjee, Rajkumar
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173500/
https://ncbi.nlm.nih.gov/pubmed/33769068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2020-0470
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