Enriched pharmacokinetic behavior and antitumor efficacy of thymoquinone by liposomal delivery

BACKGROUND: Thymoquinone (TQ) has potential anti-inflammatory, immunomodulatory and anticancer effects but its clinical use is limited by its low solubility, poor bioavailability and rapid clearance. AIM: To enhance systemic bioavailability and tumor-specific toxicity of TQ. MATERIALS & METHODS:...

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Dades bibliogràfiques
Publicat a:Nanomedicine (Lond)
Autors principals: Rachamalla, Hari Krishnareddy, Bhattacharya, Santanu, Ahmad, Ajaz, Sridharan, Kathyayani, Madamsetty, Vijay Sagar, Mondal, Sujan Kumar, Wang, Enfeng, Dutta, Shamit K, Jan, Basit L, Jinka, Sudhakar, Chandra Sekhar Jaggarapu, Madan Mohan, Yakati, Venu, Mukhopadhyay, Debabrata, Alkharfy, Khalid M, Banerjee, Rajkumar
Format: Artigo
Idioma:Inglês
Publicat: Future Medicine Ltd 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173500/
https://ncbi.nlm.nih.gov/pubmed/33769068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm-2020-0470
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