An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

Intratumoral hypoxia is a widely established element of the pancreatic tumor microenvironment (TME) promoting immune escape, tumor invasion, and progression, while contributing to treatment resistance and poor survival. Despite this critical role, hypoxia is underrepresented in molecular signatures...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Abou Khouzam, Raefa, Rao, Shyama Prasad, Venkatesh, Goutham Hassan, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Meylan, Maxime, Nimmakayalu, Manjunath, Terry, Stéphane, Chouaib, Salem
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173254/
https://ncbi.nlm.nih.gov/pubmed/34093582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.680435
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