An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

Intratumoral hypoxia is a widely established element of the pancreatic tumor microenvironment (TME) promoting immune escape, tumor invasion, and progression, while contributing to treatment resistance and poor survival. Despite this critical role, hypoxia is underrepresented in molecular signatures...

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Foilsithe in:Front Immunol
Main Authors: Abou Khouzam, Raefa, Rao, Shyama Prasad, Venkatesh, Goutham Hassan, Zeinelabdin, Nagwa Ahmed, Buart, Stephanie, Meylan, Maxime, Nimmakayalu, Manjunath, Terry, Stéphane, Chouaib, Salem
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Immunology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8173254/
https://ncbi.nlm.nih.gov/pubmed/34093582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.680435
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