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Hypoxia increases melanoma-associated fibroblasts immunosuppressive potential and inhibitory effect on T cell-mediated cytotoxicity

Cancer-associated fibroblasts (CAFs) and hypoxia are central players in the complex process of tumor cell-stroma interaction and are involved in the alteration of the anti-tumor immune response by impacting both cancer and immune cell populations. However, even if their independent immunomodulatory...

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Vydáno v:Oncoimmunology
Hlavní autoři: Ziani, Linda, Buart, Stéphanie, Chouaib, Salem, Thiery, Jerome
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8312612/
https://ncbi.nlm.nih.gov/pubmed/34367731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1950953
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