Proteasome Stress in Skeletal Muscle Mounts a Long-Range Protective Response that Delays Retinal and Brain Aging

Neurodegeneration in the central nervous system (CNS) is a defining feature of organismal aging that is influenced by peripheral tissues. Clinical observations indicate that skeletal muscle influences CNS aging but the underlying muscle-to-brain signaling remains unexplored. In Drosophila, we find t...

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Bibliografske podrobnosti
izdano v:Cell Metab
Main Authors: Rai, Mamta, Coleman, Zane, Curley, Michelle, Nityanandam, Anjana, Platt, Anna, Robles-Murguia, Maricela, Jiao, Jianqin, Finkelstein, David, Wang, Yong-Dong, Xu, Beisi, Fan, Yiping, Demontis, Fabio
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172468/
https://ncbi.nlm.nih.gov/pubmed/33773104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2021.03.005
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