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Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system

The GeneSwitch (GS) is a modified Gal4/UAS system, whereby transgene expression is induced in Drosophila by adding the drug RU486 to food. The GS system is routinely used in Drosophila aging and behavioral studies to avoid confounding effects related to genetic background mutations. Here, we report...

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Detalles Bibliográficos
Publicado en:NPJ Aging Mech Dis
Main Authors: Robles-Murguia, Maricela, Hunt, Liam C., Finkelstein, David, Fan, Yiping, Demontis, Fabio
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529481/
https://ncbi.nlm.nih.gov/pubmed/31123597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41514-019-0036-8
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