Prime-boost vaccination of mice and rhesus macaques with two novel adenovirus vectored COVID-19 vaccine candidates

COVID-19 vaccines are being developed urgently worldwide. Here, we constructed two adenovirus vectored COVID-19 vaccine candidates of Sad23L-nCoV-S and Ad49L-nCoV-S carrying the full-length gene of SARS-CoV-2 spike protein. The immunogenicity of two vaccines was individually evaluated in mice. Speci...

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Bibliografiske detaljer
Udgivet i:Emerg Microbes Infect
Main Authors: Luo, Shengxue, Zhang, Panli, Liu, Bochao, Yang, Chan, Liang, Chaolan, Wang, Qi, Zhang, Ling, Tang, Xi, Li, Jinfeng, Hou, Shuiping, Zeng, Jinfeng, Fu, Yongshui, Allain, Jean-Pierre, Li, Tingting, Zhang, Yuming, Li, Chengyao
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2021
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172228/
https://ncbi.nlm.nih.gov/pubmed/33993845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2021.1931466
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