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mRNA Transfection Retrofits Cell-based Assays with Xenobiotic Metabolism
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS assays have limited or no xenobiotic metabolism which could lead to false positive (chemical is detoxified in...
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| Vydáno v: | J Pharmacol Toxicol Methods |
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| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8171331/ https://ncbi.nlm.nih.gov/pubmed/29555536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vascn.2018.03.002 |
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