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The Alginate Immobilization of Metabolic Enzymes Platform Retrofits an Estrogen Receptor Transactivation Assay With Metabolic Competence

The U.S. EPA Endocrine Disruptor Screening Program utilizes data across the ToxCast/Tox21 high-throughput screening (HTS) programs to evaluate the biological effects of potential endocrine active substances. A potential limitation to the use of in vitro assay data in regulatory decision-making is th...

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Publicado en:Toxicol Sci
Main Authors: Deisenroth, Chad, DeGroot, Danica E., Zurlinden, Todd, Eicher, Andrew, McCord, James, Lee, Mi-Young, Carmichael, Paul, Thomas, Russell S.
Formato: Artigo
Idioma:Inglês
Publicado: 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154005/
https://ncbi.nlm.nih.gov/pubmed/32991717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa147
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