Structure of human factor VIIa–soluble tissue factor with calcium, magnesium and rubidium

Coagulation factor VIIa (FVIIa) consists of a γ-carboxyglutamic acid (GLA) domain, two epidermal growth factor-like (EGF) domains and a protease domain. FVIIa binds three Mg(2+) ions and four Ca(2+) ions in the GLA domain, one Ca(2+) ion in the EGF1 domain and one Ca(2+) ion in the protease domain....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Acta Crystallogr D Struct Biol
Prif Awduron: Vadivel, Kanagasabai, Schmidt, Amy E., Cascio, Duilio, Padmanabhan, Kaillathe, Krishnaswamy, Sriram, Brandstetter, Hans, Bajaj, S. Paul
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: International Union of Crystallography 2021
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8171065/
https://ncbi.nlm.nih.gov/pubmed/34076594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798321003922
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