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Plasmin-mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

BACKGROUND: Factor (F) IX/IXa inactivation by plasmin has been studied; however, whether plasmin converts FIXa to a fibrinolytic enhancer is not known. OBJECTIVE: Investigate plasmin proteolysis site(s) in FIXa that inactivates and transforms it into a fibrinolytic enhancer. METHODS: NH(2)-terminal...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Thromb Haemost
Päätekijät: Schmidt, Amy E., Vadivel, Kanagasabai, Whitelegge, Julian, Bajaj, S. Paul
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7363452/
https://ncbi.nlm.nih.gov/pubmed/32073726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14773
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