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Impaired Vitamin D Signaling in T Cells From a Family With Hereditary Vitamin D Resistant Rickets
The active form of vitamin D, 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), mediates its immunomodulatory effects by binding to the vitamin D receptor (VDR). Here, we describe a new point mutation in the DNA-binding domain of the VDR and its consequences for 1,25(OH)(2)D(3) signaling in T cells from...
שמור ב:
| הוצא לאור ב: | Front Immunol |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2021
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8170129/ https://ncbi.nlm.nih.gov/pubmed/34093587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.684015 |
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