SAA1/TLR2 axis directs chemotactic migration of hepatic stellate cells responding to injury

Hepatic stellate cells (HSCs) are crucial for liver injury repair and cirrhosis. However, the mechanism of chemotactic recruitment of HSCs into injury loci is still largely unknown. Here, we demonstrate that serum amyloid A1 (SAA1) acts as a chemokine recruiting HSCs toward injury loci signaling via...

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Publicado no:iScience
Main Authors: Getachew, Anteneh, Abbas, Nasir, You, Kai, Yang, Zhen, Hussain, Muzammal, Huang, Xinping, Cheng, Ziqi, Tan, Shenglin, Tao, Jiawang, Yu, Xiaorui, Chen, Yan, Yang, Fan, Pan, Tingcai, Xu, Yingying, Xu, Guosheng, Zhuang, Yuanqi, Wu, FeiMa, Li, Yinxiong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169952/
https://ncbi.nlm.nih.gov/pubmed/34113824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2021.102483
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