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TLR9 ligation in pancreatic stellate cells promotes tumorigenesis

Modulation of Toll-like receptor (TLR) signaling can have protective or protumorigenic effects on oncogenesis depending on the cancer subtype and on specific inflammatory elements within the tumor milieu. We found that TLR9 is widely expressed early during the course of pancreatic transformation and...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Exp Med
Päätekijät: Zambirinis, Constantinos P., Levie, Elliot, Nguy, Susanna, Avanzi, Antonina, Barilla, Rocky, Xu, Yijie, Seifert, Lena, Daley, Donnele, Greco, Stephanie H., Deutsch, Michael, Jonnadula, Saikiran, Torres-Hernandez, Alejandro, Tippens, Daniel, Pushalkar, Smruti, Eisenthal, Andrew, Saxena, Deepak, Ahn, Jiyoung, Hajdu, Cristina, Engle, Dannielle D., Tuveson, David, Miller, George
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647258/
https://ncbi.nlm.nih.gov/pubmed/26481685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142162
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