TLR9 ligation in pancreatic stellate cells promotes tumorigenesis

Modulation of Toll-like receptor (TLR) signaling can have protective or protumorigenic effects on oncogenesis depending on the cancer subtype and on specific inflammatory elements within the tumor milieu. We found that TLR9 is widely expressed early during the course of pancreatic transformation and...

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Veröffentlicht in:J Exp Med
Hauptverfasser: Zambirinis, Constantinos P., Levie, Elliot, Nguy, Susanna, Avanzi, Antonina, Barilla, Rocky, Xu, Yijie, Seifert, Lena, Daley, Donnele, Greco, Stephanie H., Deutsch, Michael, Jonnadula, Saikiran, Torres-Hernandez, Alejandro, Tippens, Daniel, Pushalkar, Smruti, Eisenthal, Andrew, Saxena, Deepak, Ahn, Jiyoung, Hajdu, Cristina, Engle, Dannielle D., Tuveson, David, Miller, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2015
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4647258/
https://ncbi.nlm.nih.gov/pubmed/26481685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20142162
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