Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19

An excessive immune response known as cytokine storm is the hallmark of severe COVID-19. The cause of this cytokine rampage is yet not known. Based on recent epidemiological evidence, we hypothesized that CD80/86 signaling is essential for this hyperinflammation, and that blocking this proinflammato...

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Udgivet i:Sci Rep
Main Authors: Julià, Antonio, Bonafonte-Pardàs, Irene, Gómez, Antonio, López-Lasanta, María, López-Corbeto, Mireia, Martínez-Mateu, Sergio H., Lladós, Jordi, Rodríguez-Nunez, Iván, Myers, Richard M., Marsal, Sara
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8169841/
https://ncbi.nlm.nih.gov/pubmed/34075090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90797-0
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