Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry

Costimulation is a fundamental principle of T-cell activation. In addition to T-cell receptor engagement, the interaction between CD80 and/or CD86 with CD28 and/or cytotoxic T-lymphocyte antigen 4 (CTLA-4) receptors is required to regulate T-cell activation and tolerance. While the importance of cos...

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Detalhes bibliográficos
Main Authors: Thiel, Markus, Wolfs, Melodie-Jo, Bauer, Stefan, Wenning, Anna S, Burckhart, Tanja, Schwarz, Eva C, Scott, Andrew M, Renner, Christoph, Hoth, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807484/
https://ncbi.nlm.nih.gov/pubmed/19824921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2009.03155.x
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